1. Rahman SM, Choudhury M, Janssen RC, Baquero KC, Miyazaki M, and Friedman JE. Loss of C/EBPβ protected mice from LXR agonist (T0901317) mediated induction of liver TG accumulation and lipogenesis but increased liver mitochondrial function. Biochem Biophys Res Commun in press
2. Synthetic FXR Agonists Induce HDL-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in CETP Transgenic LDLR-/- Mice. Hambruch E, Miyazaki-Anzai S, Hahn U, Matysik S, Boettcher A, Perovic-Ottstadt S, Schlueter T, Kinzel O, Krol HD, Deuschle U, Burnet M, Levi M, Schmitz G, Miyazaki M, Kremoser C J Pharmacol Exp Ther 2012 343:556-567
3. Masuda M, Ting TC, Levi M, Saunders JS, Miyazaki-Anzai S, Miyazaki M. Activating transcription factor 4 regulates stearate-induced vascular calcification J Lipid Res. 2012 53:1543-1552.
4. Tanabe K, Tamura Y, Lanaspa MA, Miyazaki M, Suzuki N, Sato W, Maeshima Y, Schreiner GF, Villarreal FJ, Johnson RJ, Nakagawa T. Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy. Am J Physiol Renal Physiol. 2012 303:F1264-74
5. Tanabe K, Lanaspa MA, Kitagawa W, Rivard CJ, Miyazaki M, Klawitter J, Schreiner GF, Saleem MA, Mathieson PW, Makino H, Johnson RJ, Nakagawa T. Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS deficient mouse. Am J Physiol Renal Physiol. 2012 302:F1151-60.
6. Ting TC, Miyazaki-Anzai S, Levi M, Demer LL, Tintut Y, and Miyazaki M, Increased Lipogenesis and Stearate Accelerate Vascular Calcification in Calcifying Vascular Cells. J. Biol Chem. 2011 286:23938-23949.
7. Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y. The role of cellular cholesterol metabolism in vascular cell calcification. J. Biol. Chem. 2011 286: 33701-33706
8. Lim RS, Suhalim JL, Miyazaki-Anzai S, Miyazaki M, Levi M, Potma EO, Tromberg BJ. Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging. J Lipid Res. 2011 52: 2177-2186
9. Miyazaki-Anzai S, Levi M, Kratzer H, Ting TC, Lewis LB, Miyazaki M. FXR activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease. Circ Res, 2010, 106, 1807-1817
10. Liu X, Miyazaki M, Flowers MT, Sampath H, Zhao M, Chu K, Paton CM, Joo DS, Ntambi JM. Loss of Stearoyl-CoA Desaturase-1 Attenuates Adipocyte Inflammation. Effects of Adipocyte-Derived Oleate. Arterioscler Thromb Vasc Biol. 2010: 2, 31-38
11. Lim RS, Kratzer A, Barry NP, Miyazaki-Anzai S, Miyazaki M, Mantulin WW, Levi M, Potma EO, Tromberg BJ.Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice. J Lipid Res 2010 51, 1729-1737
12. Dobrzyn A. Miyazaki M Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin deficient mice J Lipid Res 2010 51:2202-2210
13. Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia J. Lipid Res. 2009; 50: 312-326
14. Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 2009 380:818-822
15. Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X and Ntambi JM Hepatic Stearoyl-CoA Desaturase-1 Knockout Protects Mice from Carbohydrate-Induced Adiposity and Hepatic Steatosis. Cell Metab. 2008, 6:484-496.
16. Chen C, Shah YM, Morimura K, Krausz KW, Miyazaki M, Richardson TA, Morgan ET, Ntambi JM, Idle JR, Gonzalez FJ. Metabolomics Reveals that Hepatic Stearoyl-CoA Desaturase 1 Downregulation Exacerbates Inflammation and Acute Colitis. Cell Metab. 2008 7:135-147.
17. Mar-Heyming R, Miyazaki M, Weissglas-Volkov D, Kolaitis NA, Sadaat N, Plaisier C, Pajukanta P, Cantor RM, de Bruin TW, Ntambi JM, Lusis AJ. Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia.Arterioscler Thromb Vasc Biol. 2008 28:1193-1199.
18. Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.J Biol Chem. 2007 282:2483-2493.
19. Zarnowski R, Miyazaki M, Dobrzyn A, Ntambi JM, Woods JP. Typing of Histoplasma capsulatum strains by fatty acid profile analysis.J Med Microbiol. 2007 56:788-797.
20. Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM. Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab. 2007 294:E357-E364.
21. Man WC, Miyazaki M, Chu K, Ntambi JM Membrane topology of mouse stearoyl-CoA desaturase 1. J Biol. Chem 2006 281:1251-1260
22. Miyazaki M, Bruggink SM, Ntambi JM. Identification of mouse palmitoyl-coenzyme A D9-desaturase.J Lipid Res. 2006 47:700-704
23. Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR.Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c.Diabetes. 2006 55:2032-2041.
24. Flowers MT, Miyazaki M, Liu X, Ntambi JM. Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance.J Clin Invest. 2006 116:1478-1481.
25. Man WC, Chu K, Miyazaki M, Ntambi JM Co-localization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. J Lipid Res. 2006 47:1928-1939
26. Chu K, Miyazaki M, Man WC, Ntambi JM, Stearoyl-CoA Desaturase 1 Deficiency Protects Against Hypertriglyceridemia and Increases Plasma HDL-cholesterol Induced by Liver X Receptor. Mol Cell Biol. 2006 26:6786-6798.
27. Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.J Lipid Res. 2006, 47:2668-2680.
28. Man WC, Miyazaki M, Chu K, Ntambi J. Co-localization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis.J Lipid Res. 2006 47:1928-1939.
29. Chu K, Miyazaki M, Man WC, Ntambi JM.Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.Mol Cell Biol. 2006 26:6786-6798.
30. Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab. 2005, 288:E381-387.
31. Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency reduces ceramide synthesis by down-regulating serine palmitoyltransferase and increasing {beta}-oxidation in skeletal muscle.Am J Physiol Endocrinol Metab. Am J Physiol Endocrinol Metab. 2005;288:E599-607.
32. Dobrzyn A, Dobrzyn P, Miyazaki M, Sampath H, Chu K, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver J Biol Chem. 2005 17;280:23356-23362.
33. Biddinger SB, Almind K, Miyazaki M, Kokkotou E, Ntambi JM, Kahn CR. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome.Diabetes. 2005;54:1314-1323.
34. Dobrzyn A, Dobrzyn P, Miyazaki M, Ntambi JM. Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues.Biochem Biophys Res Commun. 2005; 332:892-896.
35. Miyazaki M, Dobrzyn A, Elias PM, Ntambi JM. Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci U S A. 2005, 102:12501-12506.
36. Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005 2:251-261.
37. Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM. Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment. J Lipid Res. 2004, 45: 1674-1678.
2. Synthetic FXR Agonists Induce HDL-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in CETP Transgenic LDLR-/- Mice. Hambruch E, Miyazaki-Anzai S, Hahn U, Matysik S, Boettcher A, Perovic-Ottstadt S, Schlueter T, Kinzel O, Krol HD, Deuschle U, Burnet M, Levi M, Schmitz G, Miyazaki M, Kremoser C J Pharmacol Exp Ther 2012 343:556-567
3. Masuda M, Ting TC, Levi M, Saunders JS, Miyazaki-Anzai S, Miyazaki M. Activating transcription factor 4 regulates stearate-induced vascular calcification J Lipid Res. 2012 53:1543-1552.
4. Tanabe K, Tamura Y, Lanaspa MA, Miyazaki M, Suzuki N, Sato W, Maeshima Y, Schreiner GF, Villarreal FJ, Johnson RJ, Nakagawa T. Epicatechin limits renal injury by mitochondrial protection in cisplatin nephropathy. Am J Physiol Renal Physiol. 2012 303:F1264-74
5. Tanabe K, Lanaspa MA, Kitagawa W, Rivard CJ, Miyazaki M, Klawitter J, Schreiner GF, Saleem MA, Mathieson PW, Makino H, Johnson RJ, Nakagawa T. Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS deficient mouse. Am J Physiol Renal Physiol. 2012 302:F1151-60.
6. Ting TC, Miyazaki-Anzai S, Levi M, Demer LL, Tintut Y, and Miyazaki M, Increased Lipogenesis and Stearate Accelerate Vascular Calcification in Calcifying Vascular Cells. J. Biol Chem. 2011 286:23938-23949.
7. Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y. The role of cellular cholesterol metabolism in vascular cell calcification. J. Biol. Chem. 2011 286: 33701-33706
8. Lim RS, Suhalim JL, Miyazaki-Anzai S, Miyazaki M, Levi M, Potma EO, Tromberg BJ. Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging. J Lipid Res. 2011 52: 2177-2186
9. Miyazaki-Anzai S, Levi M, Kratzer H, Ting TC, Lewis LB, Miyazaki M. FXR activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease. Circ Res, 2010, 106, 1807-1817
10. Liu X, Miyazaki M, Flowers MT, Sampath H, Zhao M, Chu K, Paton CM, Joo DS, Ntambi JM. Loss of Stearoyl-CoA Desaturase-1 Attenuates Adipocyte Inflammation. Effects of Adipocyte-Derived Oleate. Arterioscler Thromb Vasc Biol. 2010: 2, 31-38
11. Lim RS, Kratzer A, Barry NP, Miyazaki-Anzai S, Miyazaki M, Mantulin WW, Levi M, Potma EO, Tromberg BJ.Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice. J Lipid Res 2010 51, 1729-1737
12. Dobrzyn A. Miyazaki M Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin deficient mice J Lipid Res 2010 51:2202-2210
13. Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia J. Lipid Res. 2009; 50: 312-326
14. Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 2009 380:818-822
15. Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X and Ntambi JM Hepatic Stearoyl-CoA Desaturase-1 Knockout Protects Mice from Carbohydrate-Induced Adiposity and Hepatic Steatosis. Cell Metab. 2008, 6:484-496.
16. Chen C, Shah YM, Morimura K, Krausz KW, Miyazaki M, Richardson TA, Morgan ET, Ntambi JM, Idle JR, Gonzalez FJ. Metabolomics Reveals that Hepatic Stearoyl-CoA Desaturase 1 Downregulation Exacerbates Inflammation and Acute Colitis. Cell Metab. 2008 7:135-147.
17. Mar-Heyming R, Miyazaki M, Weissglas-Volkov D, Kolaitis NA, Sadaat N, Plaisier C, Pajukanta P, Cantor RM, de Bruin TW, Ntambi JM, Lusis AJ. Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia.Arterioscler Thromb Vasc Biol. 2008 28:1193-1199.
18. Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.J Biol Chem. 2007 282:2483-2493.
19. Zarnowski R, Miyazaki M, Dobrzyn A, Ntambi JM, Woods JP. Typing of Histoplasma capsulatum strains by fatty acid profile analysis.J Med Microbiol. 2007 56:788-797.
20. Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM. Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab. 2007 294:E357-E364.
21. Man WC, Miyazaki M, Chu K, Ntambi JM Membrane topology of mouse stearoyl-CoA desaturase 1. J Biol. Chem 2006 281:1251-1260
22. Miyazaki M, Bruggink SM, Ntambi JM. Identification of mouse palmitoyl-coenzyme A D9-desaturase.J Lipid Res. 2006 47:700-704
23. Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR.Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c.Diabetes. 2006 55:2032-2041.
24. Flowers MT, Miyazaki M, Liu X, Ntambi JM. Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance.J Clin Invest. 2006 116:1478-1481.
25. Man WC, Chu K, Miyazaki M, Ntambi JM Co-localization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. J Lipid Res. 2006 47:1928-1939
26. Chu K, Miyazaki M, Man WC, Ntambi JM, Stearoyl-CoA Desaturase 1 Deficiency Protects Against Hypertriglyceridemia and Increases Plasma HDL-cholesterol Induced by Liver X Receptor. Mol Cell Biol. 2006 26:6786-6798.
27. Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.J Lipid Res. 2006, 47:2668-2680.
28. Man WC, Miyazaki M, Chu K, Ntambi J. Co-localization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis.J Lipid Res. 2006 47:1928-1939.
29. Chu K, Miyazaki M, Man WC, Ntambi JM.Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.Mol Cell Biol. 2006 26:6786-6798.
30. Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab. 2005, 288:E381-387.
31. Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency reduces ceramide synthesis by down-regulating serine palmitoyltransferase and increasing {beta}-oxidation in skeletal muscle.Am J Physiol Endocrinol Metab. Am J Physiol Endocrinol Metab. 2005;288:E599-607.
32. Dobrzyn A, Dobrzyn P, Miyazaki M, Sampath H, Chu K, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver J Biol Chem. 2005 17;280:23356-23362.
33. Biddinger SB, Almind K, Miyazaki M, Kokkotou E, Ntambi JM, Kahn CR. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome.Diabetes. 2005;54:1314-1323.
34. Dobrzyn A, Dobrzyn P, Miyazaki M, Ntambi JM. Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues.Biochem Biophys Res Commun. 2005; 332:892-896.
35. Miyazaki M, Dobrzyn A, Elias PM, Ntambi JM. Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci U S A. 2005, 102:12501-12506.
36. Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005 2:251-261.
37. Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM. Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment. J Lipid Res. 2004, 45: 1674-1678.